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Another study that looked at anti-cancer effects of HOTYR is found in the inhibition of growth and cell proliferation in Sprague Dawley rats with experimental mammary tumors (103)

Vitamin C, selenium, and alpha-lipoic acid are also known to support glutathione activity

This protective effect is further supported by observations that GPX4 levels are diminished in cardiomyocytes of patients with diabetic heart disease [219], suggesting therapies of ferroptosis antioxidants have shown promise in alleviating diabetes-induced oxidative stress and cardiac dysfunction

5) L-Carnitine is proved to be safe and healthy food after security experiments in many countries

Other antioxidants like vitamin C, or skin-lightening agents like tranexamic acid, vitamin A (retinoids), azelaic acid, etc., have evidence for improving skin tone and might be safer choices depending on your profile